diff --git a/src/init.cpp b/src/init.cpp
index 82ebefa20..cd44128ea 100644
--- a/src/init.cpp
+++ b/src/init.cpp
@@ -1134,6 +1134,14 @@ bool AppInit2(boost::thread_group& threadGroup, CScheduler& scheduler)
             LogPrintf("%s: parameter interaction: -externalip set -> setting -discover=0\n", __func__);
     }
 
+    if(mapMultiArgs["-disableipv6"].size() > 1) {
+        return InitError("-disableipv6 can only be used once");
+    }
+
+    if(mapMultiArgs["-disableipv4"].size() > 1) {
+        return InitError("-disableipv4 can only be used once");
+    }
+
     if (GetBoolArg("-disableipv6", DEFAULT_DISABLE_IPV6)) {
         SetReachable(NET_IPV6, false);
     }